My project
Cyclocarbamte Antibiotics: Building Innovative Lead Structures through Organic Synthesis (CABILOS)
The aim of this project is the development and evaluation of a novel lead structure for small molecule therapeutics against A. baumannii and potentially also other drug resistant pathogenic bacteria such as S. aureus and P. aeruginosa which depend on the Clp protease for pathogenicity. This will be achieved through the design and organic synthesis of strained (7/8/9-membered unsaturated) cyclic carbamates with different functionality. The molecules will be designed and optimized to target the active site of Clp protease, a key enzyme involved in pathogenicity of the main target A. baumannii as well as also in other relevant bacteria such as S. aureus and P. aeruginosa.
My publications
“Endoperoxides in combating bacterial infections: synthetic pathways, mechanism, biological activity and mode of action,” published in the European Journal of Medicinal Chemistry Reports (April 2026, Volume 16, Article 100329)
My events and conferences
European Researcher Night 2025 – Barcelona
Merch Organic Chemistry Symposium 2025
My videos